Friday, May 30, 2014

Legionnaire’s Disease


As many of you may have heard, recently there have been several cases of Legionnaire’s Disease diagnosed at UAB Hospital in Downtown Birmingham, Alabama.  I thought that for this week’s topic, I would give some background information about this condition and the causative pathogen for this disease.

Legionnaire’s Disease is a type of pneumonia brought about by an infection of a bacterium from the Legionella genus.  These organisms can be found in virtually any source of water, and are likewise transferred through inhalation of water droplets that contain the pathogen, not person to person.  The disease has an incubation time of two to ten days and is characterized by symptoms that are similar to other types of bacterial pneumonia which may include fever, headache, and nonproductive cough.  The individuals at the highest risk of infection for this disease include the elderly, smokers, and those who are immunocompromised, while those with a healthy immune system either fight off the bacteria and never get Legionnaire’s Disease or only get a milder case.1

When you combine the facts, it is clear how an outbreak can easily happen in a hospital environment.  Many of the individuals have a weakened immune system, and if exposed to the Legionella bacterium in the water supply, they can easily contract this disease. 

Diagnosis of this disease is accomplished through a variety of means such as special fluorescent stains, DNA detection, and even a urine antigen test.  Since this organism is difficult to grow and isolate on standard media, special media must be utilized that can aid in its culture.1

Hopefully this information helped in the understanding of this disease.

References:

1.      Tillie, Patricia M (2014). Legionella. Bailey and Scott’s Diagnostic Microbiology 13th Edition (pp. 424-430). St. Louis, Missouri: Elsevier Mosby.

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