Friday, July 18, 2014

"It Came From Africa"-A Case Study


As our semester comes to a close, we have been covering parasites of all shapes, sizes, and types.  I have really enjoyed reading the case studies on the CDC website, like the one I shared last week, and thought that I would continue by sharing another which involves someone who contracted a parasite during a trip to Africa.

As with any case study, the narrative and patient history are the most important parts, so that is where this begins.

Case #362 - December, 2013

“A 29-year-old female post-graduate student in Zoology went on an expedition to see the lowland gorillas in the Democratic Republic of Congo. She reported numerous insect bites while traveling but did take anti-malarial prophylaxis. Approximately one week after returning home she developed fever. About a month later, she started experiencing headaches, itchy skin, and swollen lymph nodes and sought medical attention. A blood specimen was collected; smears made and stained with Wright-Giemsa.”1
 
 
 
"Case #362 – December, 2013." DPDx - Laboratory Identification of Parasitic Diseases of Public Health Concern (Figure D)
 


 


Based off the findings of the peripheral blood smear and the organisms which were observed as well as the case history, the diagnosis was Trypanosoma brucei; most probably the Trypanosoma brucei gambiense subspecies due to the geographic location of where the individual traveled.1
These organisms are transferred to humans by the bite of the Tsetse fly, which allows an immature stage of the organism’s life cycle to be introduced to the human host.  Symptoms can range from headaches, like the individual in the case study, to coma/death once more central nervous system involvement occurs.
Treatment of this disease depends on what disease stage that the organism has been able to progress; such as whether it has crossed the blood brain barrier or is just in the blood stream.2  The drugs used to treat this type of infection are typically only available from the Centers for Disease Control.2  After treatment, an infected individual will need to have repetitive examinations of their cerebral spinal fluid in order to rule out a relapse of the disease.2
 

Works Cited

1.       "Case #362 – December, 2013." DPDx - Laboratory Identification of Parasitic Diseases of Public Health Concern. CDC, November 29, 2013. Web. 18 July 2014.
 
2.       "Parasites - African Trypanosomiasis (also known as Sleeping Sickness)." Centers for Disease Control and Prevention. CDC, August 29, 2013. Web. 18 July 2014.
 

 

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